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Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals
The ε4 allele of the gene Apolipoprotein E is the major genetic risk factor for Alzheimer's Disease. APOE ε4 has been associated with changes in brain structure in cognitively impaired and unimpaired subjects, including atrophy of the hippocampus, which is one of the brain structures that is ea...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721244/ https://www.ncbi.nlm.nih.gov/pubmed/33017488 http://dx.doi.org/10.1002/hbm.25202 |