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Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals

The ε4 allele of the gene Apolipoprotein E is the major genetic risk factor for Alzheimer's Disease. APOE ε4 has been associated with changes in brain structure in cognitively impaired and unimpaired subjects, including atrophy of the hippocampus, which is one of the brain structures that is ea...

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Detalles Bibliográficos
Autores principales: Martí‐Juan, Gerard, Sanroma‐Guell, Gerard, Cacciaglia, Raffaele, Falcon, Carles, Operto, Grégory, Molinuevo, José Luis, González Ballester, Miguel Ángel, Gispert, Juan Domingo, Piella, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721244/
https://www.ncbi.nlm.nih.gov/pubmed/33017488
http://dx.doi.org/10.1002/hbm.25202