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Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected

In Alzheimer’s disease (AD), tau phosphorylation in the brain and its subsequent release into cerebrospinal fluid (CSF) and blood is a dynamic process that changes during disease evolution. The main aim of our study was to characterize the pattern of changes in phosphorylated tau (p‐tau) in the prec...

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Detalles Bibliográficos
Autores principales: Suárez‐Calvet, Marc, Karikari, Thomas K, Ashton, Nicholas J, Lantero Rodríguez, Juan, Milà‐Alomà, Marta, Gispert, Juan Domingo, Salvadó, Gemma, Minguillon, Carolina, Fauria, Karine, Shekari, Mahnaz, Grau‐Rivera, Oriol, Arenaza‐Urquijo, Eider M, Sala‐Vila, Aleix, Sánchez‐Benavides, Gonzalo, González‐de‐Echávarri, José Maria, Kollmorgen, Gwendlyn, Stoops, Erik, Vanmechelen, Eugeen, Zetterberg, Henrik, Blennow, Kaj, Molinuevo, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721364/
https://www.ncbi.nlm.nih.gov/pubmed/33169916
http://dx.doi.org/10.15252/emmm.202012921