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Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells

Evaluation of sepsis-induced immunoparalysis has highlighted how decreased lymphocyte number/function contribute to worsened infection/cancer. Yet, an interesting contrast exists with autoimmune disease development, wherein diminishing pathogenic effectors may benefit the post-septic host. Within th...

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Detalles Bibliográficos
Autores principales:	Jensen, Isaac J, Jensen, Samantha N, Sjaastad, Frances V, Gibson-Corley, Katherine N, Dileepan, Thamothrampillai, Griffith, Thomas S, Mangalam, Ashutosh K, Badovinac, Vladimir P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721438/ https://www.ncbi.nlm.nih.gov/pubmed/33191915 http://dx.doi.org/10.7554/eLife.55800

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