Small molecule cognitive enhancer reverses age-related memory decline in mice

With increased life expectancy, age-associated cognitive decline becomes a growing concern, even in the absence of recognizable neurodegenerative disease. The integrated stress response (ISR) is activated during aging and contributes to age-related brain phenotypes. We demonstrate that treatment wit...

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Detalles Bibliográficos
Autores principales: Krukowski, Karen, Nolan, Amber, Frias, Elma S, Boone, Morgane, Ureta, Gonzalo, Grue, Katherine, Paladini, Maria-Serena, Elizarraras, Edward, Delgado, Luz, Bernales, Sebastian, Walter, Peter, Rosi, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721440/
https://www.ncbi.nlm.nih.gov/pubmed/33258451
http://dx.doi.org/10.7554/eLife.62048

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