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Neurophysiological method of micro sampling of endogenous substances and their transfer from one structure to another brain structure

A fundamentally new priority method has been developed for the microsampling of endogenous substances from one brain structure for their subsequent introduction into another brain structure. The same universal capillary is first used to extract endogenous substances located in a certain brain struct...

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Detalles Bibliográficos
Autor principal: Yumatov, Evgeny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721623/
https://www.ncbi.nlm.nih.gov/pubmed/33313436
http://dx.doi.org/10.1016/j.heliyon.2020.e05648
Descripción
Sumario:A fundamentally new priority method has been developed for the microsampling of endogenous substances from one brain structure for their subsequent introduction into another brain structure. The same universal capillary is first used to extract endogenous substances located in a certain brain structure, and then the same capillary is used to transfer collected substances to another brain structure by increasing the pressure in the capillary when the laser beam heats up its closed cavity located outside. The method can be used to study the neurochemical mechanisms of the formation of emotional-motivational and pathological conditions, and identify specific endogenous substances involved in these processes. The developed method can be used in neurophysiological, psychophysiological, pharmacological, biochemical studies, as well as in molecular biology.