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Increased Sirt1 secreted from visceral white adipose tissue is associated with improved glucose tolerance in obese Nrf2-deficient mice
Obesity is associated with metabolic dysregulation characterized by insulin resistance and glucose intolerance. Nuclear factor E2-related factor (Nrf2) is a critical regulator of the stress response and Nrf2-deficient mice (Nrf2(−/−)) are protected against high fat diet (HFD)-induced metabolic deran...
Autores principales: | Braud, Laura, Pini, Maria, Stec, Donald F., Manin, Sylvie, Derumeaux, Geneviève, Stec, David E., Foresti, Roberta, Motterlini, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721645/ https://www.ncbi.nlm.nih.gov/pubmed/33285413 http://dx.doi.org/10.1016/j.redox.2020.101805 |
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