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Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells

Most T lymphocytes leave the thymus as naïve cells with limited functionality. However, unique populations of innate-like T cells differentiate into functionally distinct effector subsets during their development in the thymus. Here, we profiled >10,000 differentiating thymic invariant natural ki...

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Detalles Bibliográficos
Autores principales: Harsha Krovi, S., Zhang, Jingjing, Michaels-Foster, Mary Jessamine, Brunetti, Tonya, Loh, Liyen, Scott-Browne, James, Gapin, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721697/
https://www.ncbi.nlm.nih.gov/pubmed/33288744
http://dx.doi.org/10.1038/s41467-020-20073-8