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Development of a penem antibiotic against Mycobacteroides abscessus

β-lactams are the most widely used antibiotic class to treat bacterial infections in humans. Mycobacteroides abscessus is an emerging pulmonary pathogen resistant to most antibiotics, including penicillins and cephalosporins. With no current FDA-approved treatment and cure rates <50%, there is a...

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Detalles Bibliográficos
Autores principales: Batchelder, Hunter R., Story-Roller, Elizabeth, Lloyd, Evan P., Kaushik, Amit, Bigelow, Kristina M., Maggioncalda, Emily C., Nuermberger, Eric L., Lamichhane, Gyanu, Townsend, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721803/
https://www.ncbi.nlm.nih.gov/pubmed/33288821
http://dx.doi.org/10.1038/s42003-020-01475-2