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Targeting macrophage priming by polyphyllin VII triggers anti-tumor immunity via STING-governed cytotoxic T-cell infiltration in lung cancer

Stimulator of interferon genes (STING) controlled innate immune pathway is essential for host defense against pathogenic infection and effective anti-tumor adaptive immunity initiation. Although macrophages transformed across diverse phenotypes play crucial roles in anti-tumor immune response, event...

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Detalles Bibliográficos
Autores principales: Yu, Jinglu, Deng, Haibin, Xu, Zhenye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721813/
https://www.ncbi.nlm.nih.gov/pubmed/33288772
http://dx.doi.org/10.1038/s41598-020-77800-w