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Isoliquiritigenin prevents hyperglycemia-induced renal injuries by inhibiting inflammation and oxidative stress via SIRT1-dependent mechanism
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the effect of ISL in protecting against the injury in ST...
Autores principales: | Huang, Xiaozhong, Shi, Yujuan, Chen, Hongjin, Le, Rongrong, Gong, Xiaohua, Xu, Ke, Zhu, Qihan, Shen, Feixia, Chen, Zimiao, Gu, Xuemei, Chen, Xiaojun, Chen, Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721869/ https://www.ncbi.nlm.nih.gov/pubmed/33288747 http://dx.doi.org/10.1038/s41419-020-03260-9 |
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