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Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
In the colon, long-term exposure to chronic inflammation drives colitis-associated colon cancer (CAC) in patients with inflammatory bowel disease. While the causal and clinical links are well established, molecular understanding of how chronic inflammation leads to the development of colon cancer is...
Autores principales: | Levi-Galibov, Oshrat, Lavon, Hagar, Wassermann-Dozorets, Rina, Pevsner-Fischer, Meirav, Mayer, Shimrit, Wershof, Esther, Stein, Yaniv, Brown, Lauren E., Zhang, Wenhan, Friedman, Gil, Nevo, Reinat, Golani, Ofra, Katz, Lior H., Yaeger, Rona, Laish, Ido, Porco, John A., Sahai, Erik, Shouval, Dror S., Kelsen, David, Scherz-Shouval, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721883/ https://www.ncbi.nlm.nih.gov/pubmed/33288768 http://dx.doi.org/10.1038/s41467-020-20054-x |
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