The E3 ligase UBR2 regulates cell death under caspase deficiency via Erk/MAPK pathway

Escape from cell death is a key event in cancer establishment/progression. While apoptosis is often considered as the main cell death pathway, upon caspase inhibition, cell death is rather delayed than blocked leading to caspase-independent cell death (CICD). Although described for years, CICD’s und...

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Detalles Bibliográficos
Autores principales: Villa, Elodie, Paul, Rachel, Meynet, Ophélie, Volturo, Sophie, Pinna, Guillaume, Ricci, Jean-Ehrland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721896/
https://www.ncbi.nlm.nih.gov/pubmed/33288741
http://dx.doi.org/10.1038/s41419-020-03258-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721896/
https://www.ncbi.nlm.nih.gov/pubmed/33288741
http://dx.doi.org/10.1038/s41419-020-03258-3

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