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The E3 ligase UBR2 regulates cell death under caspase deficiency via Erk/MAPK pathway
Escape from cell death is a key event in cancer establishment/progression. While apoptosis is often considered as the main cell death pathway, upon caspase inhibition, cell death is rather delayed than blocked leading to caspase-independent cell death (CICD). Although described for years, CICD’s und...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721896/ https://www.ncbi.nlm.nih.gov/pubmed/33288741 http://dx.doi.org/10.1038/s41419-020-03258-3 |