Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis

Rolling neutrophils form tethers with submicron diameters. Here, we report that these tethers detach, forming elongated neutrophil-derived structures (ENDS) in the vessel lumen. We studied ENDS formation in mice and humans in vitro and in vivo. ENDS do not contain mitochondria, endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Marki, Alex, Buscher, Konrad, Lorenzini, Cristina, Meyer, Matthew, Saigusa, Ryosuke, Fan, Zhichao, Yeh, Yi-Ting, Hartmann, Nadine, Dan, Jennifer M., Kiosses, William B., Golden, Gregory J., Ganesan, Rajee, Winkels, Holger, Orecchioni, Marco, McArdle, Sara, Mikulski, Zbigniew, Altman, Yoav, Bui, Jack, Kronenberg, Mitchell, Chien, Shu, Esko, Jeffrey D., Nizet, Victor, Smalley, David, Roth, Johannes, Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721910/
https://www.ncbi.nlm.nih.gov/pubmed/33275138
http://dx.doi.org/10.1084/jem.20200551

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