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Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival

Complex neural circuitry requires stable connections formed by lengthy axons. To maintain these functional circuits, fast transport delivers RNAs to distal axons where they undergo local translation. However, the mechanism that enables long-distance transport of RNA granules is not yet understood. H...

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Detalles Bibliográficos
Autores principales:	Fukuda, Yusuke, Pazyra-Murphy, Maria F., Silagi, Elizabeth S., Tasdemir-Yilmaz, Ozge E., Li, Yihang, Rose, Lillian, Yeoh, Zoe C., Vangos, Nicholas E., Geffken, Ezekiel A., Seo, Hyuk-Soo, Adelmant, Guillaume, Bird, Gregory H., Walensky, Loren D., Marto, Jarrod A., Dhe-Paganon, Sirano, Segal, Rosalind A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721913/ https://www.ncbi.nlm.nih.gov/pubmed/33284322 http://dx.doi.org/10.1083/jcb.202005051

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