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Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease

OBJECTIVE: Expression of the translocator protein (TSPO) on inflammatory cells has facilitated imaging of synovitis with TSPO-targeted positron emission tomography (PET). We aimed to quantitatively assess the specificity of the second-generation TSPO PET radioligand, [(11)C]PBR28, and to generate si...

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Detalles Bibliográficos
Autores principales: Helo, Yusuf, Searle, Graham E., Borghese, Federica, Abraham, Sonya, Saleem, Azeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721924/
https://www.ncbi.nlm.nih.gov/pubmed/33284369
http://dx.doi.org/10.1186/s13550-020-00736-9