Malignant phyllodes tumor of the breast with rapid progression: a case report

BACKGROUND: Malignant phyllodes tumors (PTs) of the breast occur infrequently and are difficult to treat with adjuvant therapy. Here, we present a case of a female patient with a huge malignant PT with rapid progression in a short period. CASE PRESENTATION: A 44-year-old woman presented to our hospi...

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Autores principales: Abe, Hajime, Teramoto, Atsuko, Takei, Yumiko, Tanaka, Yoshihito, Yoneda, Genichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721958/
https://www.ncbi.nlm.nih.gov/pubmed/33284362
http://dx.doi.org/10.1186/s40792-020-00986-8
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author Abe, Hajime
Teramoto, Atsuko
Takei, Yumiko
Tanaka, Yoshihito
Yoneda, Genichiro
author_facet Abe, Hajime
Teramoto, Atsuko
Takei, Yumiko
Tanaka, Yoshihito
Yoneda, Genichiro
author_sort Abe, Hajime
collection PubMed
description BACKGROUND: Malignant phyllodes tumors (PTs) of the breast occur infrequently and are difficult to treat with adjuvant therapy. Here, we present a case of a female patient with a huge malignant PT with rapid progression in a short period. CASE PRESENTATION: A 44-year-old woman presented to our hospital with a rapid growth mass in her right breast, measuring 20 cm. She was initially diagnosed as having a borderline phyllodes tumor by core needle biopsy and underwent total mastectomy and artificial dermis was grafted, 20 days later, latissimus dorsi muscle flap and free skin grafting were performed. Two courses of doxorubicin–ifosfamide therapy were administered because of recurrence, but the patient died 4 months after the mastectomy. CONCLUSIONS: A standard therapeutic strategy for malignant PTs is needed in urgently to reduce the risk of tumor recurrence.
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spelling pubmed-77219582020-12-11 Malignant phyllodes tumor of the breast with rapid progression: a case report Abe, Hajime Teramoto, Atsuko Takei, Yumiko Tanaka, Yoshihito Yoneda, Genichiro Surg Case Rep Case Report BACKGROUND: Malignant phyllodes tumors (PTs) of the breast occur infrequently and are difficult to treat with adjuvant therapy. Here, we present a case of a female patient with a huge malignant PT with rapid progression in a short period. CASE PRESENTATION: A 44-year-old woman presented to our hospital with a rapid growth mass in her right breast, measuring 20 cm. She was initially diagnosed as having a borderline phyllodes tumor by core needle biopsy and underwent total mastectomy and artificial dermis was grafted, 20 days later, latissimus dorsi muscle flap and free skin grafting were performed. Two courses of doxorubicin–ifosfamide therapy were administered because of recurrence, but the patient died 4 months after the mastectomy. CONCLUSIONS: A standard therapeutic strategy for malignant PTs is needed in urgently to reduce the risk of tumor recurrence. Springer Berlin Heidelberg 2020-12-07 /pmc/articles/PMC7721958/ /pubmed/33284362 http://dx.doi.org/10.1186/s40792-020-00986-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Case Report
Abe, Hajime
Teramoto, Atsuko
Takei, Yumiko
Tanaka, Yoshihito
Yoneda, Genichiro
Malignant phyllodes tumor of the breast with rapid progression: a case report
title Malignant phyllodes tumor of the breast with rapid progression: a case report
title_full Malignant phyllodes tumor of the breast with rapid progression: a case report
title_fullStr Malignant phyllodes tumor of the breast with rapid progression: a case report
title_full_unstemmed Malignant phyllodes tumor of the breast with rapid progression: a case report
title_short Malignant phyllodes tumor of the breast with rapid progression: a case report
title_sort malignant phyllodes tumor of the breast with rapid progression: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721958/
https://www.ncbi.nlm.nih.gov/pubmed/33284362
http://dx.doi.org/10.1186/s40792-020-00986-8
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