Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

BACKGROUND: Circular RNAs (circRNAs) are stable, often highly expressed RNA transcripts with potential to modulate other regulatory RNAs. A few circRNAs have been shown to bind RNA-binding proteins (RBPs); however, little is known about the prevalence and distribution of these interactions in differ...

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Detalles Bibliográficos
Autores principales: Okholm, Trine Line Hauge, Sathe, Shashank, Park, Samuel S., Kamstrup, Andreas Bjerregaard, Rasmussen, Asta Mannstaedt, Shankar, Archana, Chua, Zong Ming, Fristrup, Niels, Nielsen, Morten Muhlig, Vang, Søren, Dyrskjøt, Lars, Aigner, Stefan, Damgaard, Christian Kroun, Yeo, Gene W., Pedersen, Jakob Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722315/
https://www.ncbi.nlm.nih.gov/pubmed/33287884
http://dx.doi.org/10.1186/s13073-020-00812-8

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