STARRPeaker: uniform processing and accurate identification of STARR-seq active regions

STARR-seq technology has employed progressively more complex genomic libraries and increased sequencing depths. An issue with the increased complexity and depth is that the coverage in STARR-seq experiments is non-uniform, overdispersed, and often confounded by sequencing biases, such as GC content....

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Detalles Bibliográficos
Autores principales: Lee, Donghoon, Shi, Manman, Moran, Jennifer, Wall, Martha, Zhang, Jing, Liu, Jason, Fitzgerald, Dominic, Kyono, Yasuhiro, Ma, Lijia, White, Kevin P., Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722316/
https://www.ncbi.nlm.nih.gov/pubmed/33292397
http://dx.doi.org/10.1186/s13059-020-02194-x

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