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Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men

BACKGROUND: Distal radius fractures can adversely affect wrist function; for men with this fracture, the role played by fracture severity, age and osteoporosis on fracture outcome has not been sufficiently studied. OBJECTIVE: To describe patient-reported outcome and the association with bone integri...

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Autores principales: Egund, Lisa, McGuigan, Fiona E., Egund, Niels, Besjakov, Jack, Åkesson, Kristina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722451/
https://www.ncbi.nlm.nih.gov/pubmed/33287782
http://dx.doi.org/10.1186/s12891-020-03843-9
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author Egund, Lisa
McGuigan, Fiona E.
Egund, Niels
Besjakov, Jack
Åkesson, Kristina E.
author_facet Egund, Lisa
McGuigan, Fiona E.
Egund, Niels
Besjakov, Jack
Åkesson, Kristina E.
author_sort Egund, Lisa
collection PubMed
description BACKGROUND: Distal radius fractures can adversely affect wrist function; for men with this fracture, the role played by fracture severity, age and osteoporosis on fracture outcome has not been sufficiently studied. OBJECTIVE: To describe patient-reported outcome and the association with bone integrity, fracture severity and future fracture risk among young and older men with distal radius fracture. METHODS: This prospective study includes 133 men with acute distal radius fracture, mean age 54 (range 21–88), who were followed for 12 months. They were categorized as younger (< 65) and older (65+). Main outcome was DASH (Disability of the Arm, Shoulder and Hand) at 12 months; DASH > 15 was defined as poor outcome. Fractures were classified and radiographic displacement identified at initial presentation and follow-up. BMD was measured and FRAX 10-year probability of fracture calculated. RESULTS: Disability was higher in older men (DASH(median) 10 vs 2; p = 0.002); a clinically meaningful difference (ΔDASH = 10, p = 0.017) remained after adjustment for displacement, fracture classification and treatment method. Almost 50% of older men vs 14% in younger had poor outcome, p < 0.001. Bone mineral density did not independently predict outcome. Older men with a displaced fracture at initial presentation had greater disability (DASH(median), IQR 45, 14;73) and risk of fracture (FRAX(major osteoporotic) 14, 8;21). CONCLUSION: Men over the age of 65 with a distal radius fracture are more likely to have post-fracture disability regardless of radiographic appearance. Fracture displacement, indicating impaired bone strength, is also more common and associated with an increased risk of fracture within 10-years. Secondary fracture prevention should therefore be considered in men presenting with distal radius fracture. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12891-020-03843-9.
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spelling pubmed-77224512020-12-08 Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men Egund, Lisa McGuigan, Fiona E. Egund, Niels Besjakov, Jack Åkesson, Kristina E. BMC Musculoskelet Disord Research Article BACKGROUND: Distal radius fractures can adversely affect wrist function; for men with this fracture, the role played by fracture severity, age and osteoporosis on fracture outcome has not been sufficiently studied. OBJECTIVE: To describe patient-reported outcome and the association with bone integrity, fracture severity and future fracture risk among young and older men with distal radius fracture. METHODS: This prospective study includes 133 men with acute distal radius fracture, mean age 54 (range 21–88), who were followed for 12 months. They were categorized as younger (< 65) and older (65+). Main outcome was DASH (Disability of the Arm, Shoulder and Hand) at 12 months; DASH > 15 was defined as poor outcome. Fractures were classified and radiographic displacement identified at initial presentation and follow-up. BMD was measured and FRAX 10-year probability of fracture calculated. RESULTS: Disability was higher in older men (DASH(median) 10 vs 2; p = 0.002); a clinically meaningful difference (ΔDASH = 10, p = 0.017) remained after adjustment for displacement, fracture classification and treatment method. Almost 50% of older men vs 14% in younger had poor outcome, p < 0.001. Bone mineral density did not independently predict outcome. Older men with a displaced fracture at initial presentation had greater disability (DASH(median), IQR 45, 14;73) and risk of fracture (FRAX(major osteoporotic) 14, 8;21). CONCLUSION: Men over the age of 65 with a distal radius fracture are more likely to have post-fracture disability regardless of radiographic appearance. Fracture displacement, indicating impaired bone strength, is also more common and associated with an increased risk of fracture within 10-years. Secondary fracture prevention should therefore be considered in men presenting with distal radius fracture. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12891-020-03843-9. BioMed Central 2020-12-07 /pmc/articles/PMC7722451/ /pubmed/33287782 http://dx.doi.org/10.1186/s12891-020-03843-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Egund, Lisa
McGuigan, Fiona E.
Egund, Niels
Besjakov, Jack
Åkesson, Kristina E.
Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
title Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
title_full Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
title_fullStr Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
title_full_unstemmed Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
title_short Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
title_sort patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722451/
https://www.ncbi.nlm.nih.gov/pubmed/33287782
http://dx.doi.org/10.1186/s12891-020-03843-9
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