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Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein
Thrombosis is a serious complication of a hyaluronic acid-based filler injection. Little is known about the late-onset complications of fillers; therefore, an optimal complication management is necessary. In this case report, we describe a rare complication of thrombosis after a filler injection. A...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722585/ https://www.ncbi.nlm.nih.gov/pubmed/33299692 http://dx.doi.org/10.1097/GOX.0000000000003216 |
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author | Gabrielpillai, Jennis Salamat, Arash Schaefer, Christian Kania, Alexander Lunatschek, Christian Eichhorn, Klaus Wolfgang Bootz, Friedrich Send, Thorsten |
author_facet | Gabrielpillai, Jennis Salamat, Arash Schaefer, Christian Kania, Alexander Lunatschek, Christian Eichhorn, Klaus Wolfgang Bootz, Friedrich Send, Thorsten |
author_sort | Gabrielpillai, Jennis |
collection | PubMed |
description | Thrombosis is a serious complication of a hyaluronic acid-based filler injection. Little is known about the late-onset complications of fillers; therefore, an optimal complication management is necessary. In this case report, we describe a rare complication of thrombosis after a filler injection. A 35-year old woman was admitted to the emergency department, with swelling on her forehead in association with recurrent pain and light flashes in her right eye. Sonographic examination showed a thrombosis of the right frontal vein. The patient reported that a hyaluronic acid filler injection had been administered on the forehead 3 months ago. After several weeks of anticoagulation with heparin and apixaban, the symptoms persisted. The vein with thrombosis was ultimately resected under local anesthesia. Histological findings showed a chronic inflammatory reaction of the tissue to hyaluronic acid. Vascular complications may appear as late-onset complications even several months after the filler injection. Subcutaneous application of low molecular weight heparins is the therapy of first choice. If this treatment is not effective, resection of the thrombosis may be performed. |
format | Online Article Text |
id | pubmed-7722585 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-77225852020-12-08 Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein Gabrielpillai, Jennis Salamat, Arash Schaefer, Christian Kania, Alexander Lunatschek, Christian Eichhorn, Klaus Wolfgang Bootz, Friedrich Send, Thorsten Plast Reconstr Surg Glob Open Cosmetic Thrombosis is a serious complication of a hyaluronic acid-based filler injection. Little is known about the late-onset complications of fillers; therefore, an optimal complication management is necessary. In this case report, we describe a rare complication of thrombosis after a filler injection. A 35-year old woman was admitted to the emergency department, with swelling on her forehead in association with recurrent pain and light flashes in her right eye. Sonographic examination showed a thrombosis of the right frontal vein. The patient reported that a hyaluronic acid filler injection had been administered on the forehead 3 months ago. After several weeks of anticoagulation with heparin and apixaban, the symptoms persisted. The vein with thrombosis was ultimately resected under local anesthesia. Histological findings showed a chronic inflammatory reaction of the tissue to hyaluronic acid. Vascular complications may appear as late-onset complications even several months after the filler injection. Subcutaneous application of low molecular weight heparins is the therapy of first choice. If this treatment is not effective, resection of the thrombosis may be performed. Lippincott Williams & Wilkins 2020-11-25 /pmc/articles/PMC7722585/ /pubmed/33299692 http://dx.doi.org/10.1097/GOX.0000000000003216 Text en Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Cosmetic Gabrielpillai, Jennis Salamat, Arash Schaefer, Christian Kania, Alexander Lunatschek, Christian Eichhorn, Klaus Wolfgang Bootz, Friedrich Send, Thorsten Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein |
title | Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein |
title_full | Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein |
title_fullStr | Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein |
title_full_unstemmed | Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein |
title_short | Hyaluronic Acid-based Filler Injection: Late-onset Thrombosis of the Frontal Vein |
title_sort | hyaluronic acid-based filler injection: late-onset thrombosis of the frontal vein |
topic | Cosmetic |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722585/ https://www.ncbi.nlm.nih.gov/pubmed/33299692 http://dx.doi.org/10.1097/GOX.0000000000003216 |
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