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Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine
AIM: Although opioids have been used as treatment of neuropathic pain, opioids have abuse potential in humans. Since soluble epoxide hydrolase (sEH) in the metabolism of polyunsaturated fatty acids plays a key role in the pain, sEH inhibitors would be promising new therapeutic drugs for neuropathic...
Autores principales: | Wan, Xiayun, Fujita, Yuko, Chang, Lijia, Wei, Yan, Ma, Li, Wuyun, Gerile, Pu, Yaoyu, Hammock, Bruce D., Hashimoto, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722641/ https://www.ncbi.nlm.nih.gov/pubmed/32896112 http://dx.doi.org/10.1002/npr2.12136 |
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