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Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder

AIM: The Wechsler Adult Intelligent Scale (WAIS) is the most frequently administered cognitive assessment for adult Attention‐deficit hyperactivity disorder (ADHD); therefore, identifying discrepancies in WAIS profile in patients and comparing with matched controls would be clinically and diagnostic...

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Autores principales: Takeda, Toshinobu, Nakashima, Youta, Tsuji, Yui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722665/
https://www.ncbi.nlm.nih.gov/pubmed/32333645
http://dx.doi.org/10.1002/npr2.12106
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author Takeda, Toshinobu
Nakashima, Youta
Tsuji, Yui
author_facet Takeda, Toshinobu
Nakashima, Youta
Tsuji, Yui
author_sort Takeda, Toshinobu
collection PubMed
description AIM: The Wechsler Adult Intelligent Scale (WAIS) is the most frequently administered cognitive assessment for adult Attention‐deficit hyperactivity disorder (ADHD); therefore, identifying discrepancies in WAIS profile in patients and comparing with matched controls would be clinically and diagnostically beneficial. METHODS: The WAIS‐III profiles of 50 adults with ADHD were compared to an age‐matched typical development (TD) group. RESULTS: The adult ADHD group exhibited significantly lower WAIS‐III working memory (WM) and processing speed (PS) indices. However, these differences disappeared when intelligence quotient (IQ), Beck Depression Inventory (BDI) score, or Autism Quotient (AQ) score was included as a covariate. The adult ADHD group also demonstrated significantly lower scores in several WM‐ and PS‐domain subscales, while crystallized abilities were comparatively preserved. Additionally, only a small portion of participants in both groups lacked any significant gaps between WAIS‐III verbal and performance IQ scores (VIQ–PIQ) or associated indices. DISCUSSION: This study confirms previous findings that adult ADHD patients have deficits in WM and PS. However, it is highly likely that comorbidities such as depression and autism spectrum disorder contribute to lower WM and PS scores in adult ADHD. Unexpectedly, a “flat profile” is uncommon even in TD adults. Therefore, clinician should assess how WAIS deficits affect daily life rather than merely considering an uneven WAIS profile when diagnosing and treating adult ADHD.
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spelling pubmed-77226652020-12-08 Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder Takeda, Toshinobu Nakashima, Youta Tsuji, Yui Neuropsychopharmacol Rep Original Articles AIM: The Wechsler Adult Intelligent Scale (WAIS) is the most frequently administered cognitive assessment for adult Attention‐deficit hyperactivity disorder (ADHD); therefore, identifying discrepancies in WAIS profile in patients and comparing with matched controls would be clinically and diagnostically beneficial. METHODS: The WAIS‐III profiles of 50 adults with ADHD were compared to an age‐matched typical development (TD) group. RESULTS: The adult ADHD group exhibited significantly lower WAIS‐III working memory (WM) and processing speed (PS) indices. However, these differences disappeared when intelligence quotient (IQ), Beck Depression Inventory (BDI) score, or Autism Quotient (AQ) score was included as a covariate. The adult ADHD group also demonstrated significantly lower scores in several WM‐ and PS‐domain subscales, while crystallized abilities were comparatively preserved. Additionally, only a small portion of participants in both groups lacked any significant gaps between WAIS‐III verbal and performance IQ scores (VIQ–PIQ) or associated indices. DISCUSSION: This study confirms previous findings that adult ADHD patients have deficits in WM and PS. However, it is highly likely that comorbidities such as depression and autism spectrum disorder contribute to lower WM and PS scores in adult ADHD. Unexpectedly, a “flat profile” is uncommon even in TD adults. Therefore, clinician should assess how WAIS deficits affect daily life rather than merely considering an uneven WAIS profile when diagnosing and treating adult ADHD. John Wiley and Sons Inc. 2020-04-25 /pmc/articles/PMC7722665/ /pubmed/32333645 http://dx.doi.org/10.1002/npr2.12106 Text en © 2020 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of NeuropsychoPharmacology. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Takeda, Toshinobu
Nakashima, Youta
Tsuji, Yui
Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder
title Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder
title_full Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder
title_fullStr Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder
title_full_unstemmed Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder
title_short Discrepancies in Wechsler Adult Intelligent Scale III profile in adult with and without attention‐deficit hyperactivity disorder
title_sort discrepancies in wechsler adult intelligent scale iii profile in adult with and without attention‐deficit hyperactivity disorder
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722665/
https://www.ncbi.nlm.nih.gov/pubmed/32333645
http://dx.doi.org/10.1002/npr2.12106
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