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Complimentary action of structured and unstructured domains of epsin supports clathrin-mediated endocytosis at high tension

Membrane tension plays an inhibitory role in clathrin-mediated endocytosis (CME) by impeding the transition of flat plasma membrane to hemispherical clathrin-coated structures (CCSs). Membrane tension also impedes the transition of hemispherical domes to omega-shaped CCSs. However, CME is not comple...

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Detalles Bibliográficos
Autores principales: Joseph, Jophin G., Osorio, Carlos, Yee, Vivian, Agrawal, Ashutosh, Liu, Allen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722716/
https://www.ncbi.nlm.nih.gov/pubmed/33293652
http://dx.doi.org/10.1038/s42003-020-01471-6