Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages

Immunosuppressive tumor microenvironment (TME) and ascites-derived spheroids in ovarian cancer (OC) facilitate tumor growth and progression, and also pose major obstacles for cancer therapy. The molecular pathways involved in the OC-TME interactions, how the crosstalk impinges on OC aggression and c...

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Detalles Bibliográficos
Autores principales: Song, Mei, Yeku, Oladapo O., Rafiq, Sarwish, Purdon, Terence, Dong, Xue, Zhu, Lijing, Zhang, Tuo, Wang, Huan, Yu, Ziqi, Mai, Junhua, Shen, Haifa, Nixon, Briana, Li, Ming, Brentjens, Renier J., Ma, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722725/
https://www.ncbi.nlm.nih.gov/pubmed/33293516
http://dx.doi.org/10.1038/s41467-020-20140-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722725/
https://www.ncbi.nlm.nih.gov/pubmed/33293516
http://dx.doi.org/10.1038/s41467-020-20140-0

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