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Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration. However, the mechanism of movement is unknown. We hypothesized t...

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Detalles Bibliográficos
Autores principales: Cray, Paul, Sheahan, Breanna J., Cortes, Jocsa E., Dekaney, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722747/
https://www.ncbi.nlm.nih.gov/pubmed/33293626
http://dx.doi.org/10.1038/s41598-020-78473-1