Total synthesis of lindbladione, a Hes1 dimerization inhibitor and neural stem cell activator isolated from Lindbladia tubulina

Lindbladione (1) is a neural stem cell differentiation activator isolated from Lindbladia tubulina by our group. Hes1 dimerization inhibitory activity of lindbladione (1) was discovered using our original fluorescent Hes1 dimer microplate assay. We also found that lindbladione (1) accelerates the di...

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Detalles Bibliográficos
Autores principales: Arai, Midori A., Makita, Yuna, Yamaguchi, Yumi, Kawano, Haruka, Suganami, Akiko, Tamura, Yutaka, Ishibashi, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722756/
https://www.ncbi.nlm.nih.gov/pubmed/33293619
http://dx.doi.org/10.1038/s41598-020-78524-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722756/
https://www.ncbi.nlm.nih.gov/pubmed/33293619
http://dx.doi.org/10.1038/s41598-020-78524-7

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