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Total synthesis of lindbladione, a Hes1 dimerization inhibitor and neural stem cell activator isolated from Lindbladia tubulina
Lindbladione (1) is a neural stem cell differentiation activator isolated from Lindbladia tubulina by our group. Hes1 dimerization inhibitory activity of lindbladione (1) was discovered using our original fluorescent Hes1 dimer microplate assay. We also found that lindbladione (1) accelerates the di...
Autores principales: | Arai, Midori A., Makita, Yuna, Yamaguchi, Yumi, Kawano, Haruka, Suganami, Akiko, Tamura, Yutaka, Ishibashi, Masami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722756/ https://www.ncbi.nlm.nih.gov/pubmed/33293619 http://dx.doi.org/10.1038/s41598-020-78524-7 |
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