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Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production

The central melanocortin system plays a fundamental role in the control of feeding and body weight. Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) also regulate overall glucose homeostasis via insulin-dependent and -independent pathways. Here, we report that a su...

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Detalles Bibliográficos
Autores principales: Kwon, Eunjin, Joung, Hye-Young, Liu, Shun-Mei, Chua, Streamson C., Schwartz, Gary J., Jo, Young-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722761/
https://www.ncbi.nlm.nih.gov/pubmed/33293550
http://dx.doi.org/10.1038/s41467-020-20160-w