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Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production
The central melanocortin system plays a fundamental role in the control of feeding and body weight. Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) also regulate overall glucose homeostasis via insulin-dependent and -independent pathways. Here, we report that a su...
Autores principales: | Kwon, Eunjin, Joung, Hye-Young, Liu, Shun-Mei, Chua, Streamson C., Schwartz, Gary J., Jo, Young-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722761/ https://www.ncbi.nlm.nih.gov/pubmed/33293550 http://dx.doi.org/10.1038/s41467-020-20160-w |
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