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The antiplatelet agent revacept prevents the increase of systemic thromboxane A(2) biosynthesis and neointima hyperplasia
Neointima hyperplasia is a crucial component of restenosis after coronary angioplasty. We have hypothesized that enhanced generation of platelet-derived thromboxane (TX)A(2) in response to vascular damage plays a critical role in neointimal hyperplasia and that antiplatelet agents may mitigate it. I...
Autores principales: | Alberti, Sara, Zhang, Qianqian, D’Agostino, Ilaria, Bruno, Annalisa, Tacconelli, Stefania, Contursi, Annalisa, Guarnieri, Simone, Dovizio, Melania, Falcone, Lorenza, Ballerini, Patrizia, Münch, Götz, Yu, Ying, Patrignani, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722842/ https://www.ncbi.nlm.nih.gov/pubmed/33293599 http://dx.doi.org/10.1038/s41598-020-77934-x |
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