Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer’s disease

Deficits in the clearance of amyloid β-protein (Aβ) play a pivotal role in the pathogenesis of sporadic Alzheimer’s disease (AD). The roles of blood monocytes in the development of AD remain unclear. In this study, we sought to investigate the alterations in the Aβ phagocytosis function of periphera...

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Detalles Bibliográficos
Autores principales: Chen, Si-Han, Tian, Ding-Yuan, Shen, Ying-Ying, Cheng, Yuan, Fan, Dong-Yu, Sun, Hao-Lun, He, Chen-Yang, Sun, Pu-Yang, Bu, Xian-Le, Zeng, Fan, Liu, Juan, Deng, Juan, Xu, Zhi-Qiang, Chen, Yang, Wang, Yan-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722845/
https://www.ncbi.nlm.nih.gov/pubmed/33293506
http://dx.doi.org/10.1038/s41398-020-01113-9

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