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Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains
Mammalian cells exhibit remarkable diversity in cell size, but the factors that regulate establishment and maintenance of these sizes remain poorly understood. This is especially true for skeletal muscle, comprised of syncytial myofibers that each accrue hundreds of nuclei during development. Here,...
Autores principales: | Cramer, Alyssa A. W., Prasad, Vikram, Eftestøl, Einar, Song, Taejeong, Hansson, Kenth-Arne, Dugdale, Hannah F., Sadayappan, Sakthivel, Ochala, Julien, Gundersen, Kristian, Millay, Douglas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722938/ https://www.ncbi.nlm.nih.gov/pubmed/33293533 http://dx.doi.org/10.1038/s41467-020-20058-7 |
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