Cargando…

Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study

Background: This study aimed to investigate the association between prenatal/infancy factors and lipid profile in children and adolescents. Methods: This multicentric national study was conducted in 30 provinces in Iran. It comprised 4200 participants, aged 7-18 years, from the fifth survey of a nat...

Descripción completa

Detalles Bibliográficos
Autores principales: Vard, Bahareh, Adham, Arefeh, Riahi, Roya, Karimi, Golgis, Esmail Motlagh, Mohammad, Heshmat, Ramin, Qorbani, Mostafa, Kelishadi, Roya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722995/
https://www.ncbi.nlm.nih.gov/pubmed/33312930
http://dx.doi.org/10.34172/hpp.2020.53
_version_ 1783620266230808576
author Vard, Bahareh
Adham, Arefeh
Riahi, Roya
Karimi, Golgis
Esmail Motlagh, Mohammad
Heshmat, Ramin
Qorbani, Mostafa
Kelishadi, Roya
author_facet Vard, Bahareh
Adham, Arefeh
Riahi, Roya
Karimi, Golgis
Esmail Motlagh, Mohammad
Heshmat, Ramin
Qorbani, Mostafa
Kelishadi, Roya
author_sort Vard, Bahareh
collection PubMed
description Background: This study aimed to investigate the association between prenatal/infancy factors and lipid profile in children and adolescents. Methods: This multicentric national study was conducted in 30 provinces in Iran. It comprised 4200 participants, aged 7-18 years, from the fifth survey of a national surveillance program. History regarding birth weight, as well as the type of consumed milk and food during infancy was obtained from parents. In addition to physical examinations, fasting blood samples were obtained to assess the lipid profile of these students. Results: Data from 3844 participants were available (91.5% participation rate), 52.4 % of students were boys. Mean (SD) age of participants was 12.3(3.2) years. Consuming cow milk in the first two years significantly increased the risk of high triglycerides (TG) (odds ratio [OR]:2.77, 95% CI: 1.32-5.85, P: 0.01), elevated low-density lipoprotein (LDL) (P<0.05) and low high-density lipoprotein (HDL) (P <0.05). Students who had consumed commercially made food as complementary feeding were 93% more likely to have high LDL (OR: 1.93, 95% CI=1.19-3.13, P: 0.01) and 90% more likely to have high TG than students who had consumed homemade food (OR: 1.90, 95% CI: 1.15-3.12, P: 0.01). The aforementioned figures were not significantly associated with an elevated total cholesterol (TC) level. Conclusion: Our findings revealed that the history of using human milk and home-made food as complementary feeding was associated with better lipid profile in childhood and early adolescence. Increasing public knowledge in this regard might be useful for encouragement of healthier life prevention of chronic diseases.
format Online
Article
Text
id pubmed-7722995
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Tabriz University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-77229952020-12-10 Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study Vard, Bahareh Adham, Arefeh Riahi, Roya Karimi, Golgis Esmail Motlagh, Mohammad Heshmat, Ramin Qorbani, Mostafa Kelishadi, Roya Health Promot Perspect Original Article Background: This study aimed to investigate the association between prenatal/infancy factors and lipid profile in children and adolescents. Methods: This multicentric national study was conducted in 30 provinces in Iran. It comprised 4200 participants, aged 7-18 years, from the fifth survey of a national surveillance program. History regarding birth weight, as well as the type of consumed milk and food during infancy was obtained from parents. In addition to physical examinations, fasting blood samples were obtained to assess the lipid profile of these students. Results: Data from 3844 participants were available (91.5% participation rate), 52.4 % of students were boys. Mean (SD) age of participants was 12.3(3.2) years. Consuming cow milk in the first two years significantly increased the risk of high triglycerides (TG) (odds ratio [OR]:2.77, 95% CI: 1.32-5.85, P: 0.01), elevated low-density lipoprotein (LDL) (P<0.05) and low high-density lipoprotein (HDL) (P <0.05). Students who had consumed commercially made food as complementary feeding were 93% more likely to have high LDL (OR: 1.93, 95% CI=1.19-3.13, P: 0.01) and 90% more likely to have high TG than students who had consumed homemade food (OR: 1.90, 95% CI: 1.15-3.12, P: 0.01). The aforementioned figures were not significantly associated with an elevated total cholesterol (TC) level. Conclusion: Our findings revealed that the history of using human milk and home-made food as complementary feeding was associated with better lipid profile in childhood and early adolescence. Increasing public knowledge in this regard might be useful for encouragement of healthier life prevention of chronic diseases. Tabriz University of Medical Sciences 2020-11-07 /pmc/articles/PMC7722995/ /pubmed/33312930 http://dx.doi.org/10.34172/hpp.2020.53 Text en © 2020 The Author(s). http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Vard, Bahareh
Adham, Arefeh
Riahi, Roya
Karimi, Golgis
Esmail Motlagh, Mohammad
Heshmat, Ramin
Qorbani, Mostafa
Kelishadi, Roya
Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study
title Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study
title_full Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study
title_fullStr Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study
title_full_unstemmed Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study
title_short Association of early life factors with dyslipidemia in children and adolescents: The CASPIAN-V study
title_sort association of early life factors with dyslipidemia in children and adolescents: the caspian-v study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722995/
https://www.ncbi.nlm.nih.gov/pubmed/33312930
http://dx.doi.org/10.34172/hpp.2020.53
work_keys_str_mv AT vardbahareh associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT adhamarefeh associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT riahiroya associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT karimigolgis associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT esmailmotlaghmohammad associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT heshmatramin associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT qorbanimostafa associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy
AT kelishadiroya associationofearlylifefactorswithdyslipidemiainchildrenandadolescentsthecaspianvstudy