BCAS2, a protein enriched in advanced prostate cancer, interacts with NBS1 to enhance DNA double-strand break repair

BACKGROUND: Breast cancer amplified sequence 2 (BCAS2) plays crucial roles in pre-mRNA splicing and androgen receptor transcription. Previous studies suggested that BCAS2 is involved in double-strand breaks (DSB); therefore, we aimed to characterise its mechanism and role in prostate cancer (PCa). M...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Li-Po, Chen, Tzu-Yu, Kang, Chun-Kai, Huang, Hsiang-Po, Chen, Show-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723048/
https://www.ncbi.nlm.nih.gov/pubmed/32963349
http://dx.doi.org/10.1038/s41416-020-01086-y

Ejemplares similares

Ejemplares similares