Clinical, metabolic, and molecular genetic characterization of hereditary methemoglobinemia caused by cytochrome b(5) reductase deficiency in 30 dogs

Genotype–phenotype correlations of humans and dogs with hereditary methemoglobinemia are not yet well characterized. We determined total hemoglobin and methemoglobin (MetHb) concentrations, cytochrome b(5) reductase (CYB5R) enzyme activities, genotypes, and clinical signs in 30 dogs with persistent...

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Detalles Bibliográficos
Autores principales: Jaffey, J. A., Reading, N. S., Abdulmalik, O., Kreisler, R., Bullock, G., Wiest, A., Villani, N. A., Mhlanga-Mutangadura, T., Johnson, G. S., Cohn, L. A., Isaza, N., Harvey, J. W., Giger, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723051/
https://www.ncbi.nlm.nih.gov/pubmed/33293645
http://dx.doi.org/10.1038/s41598-020-78391-2

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