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RNA structure-wide discovery of functional interactions with multiplexed RNA motif library

Biochemical assays and computational analyses have discovered RNA structures throughout various transcripts. However, the roles of these structures are mostly unknown. Here we develop folded RNA element profiling with structure library (FOREST), a multiplexed affinity assay system to identify functi...

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Detalles Bibliográficos
Autores principales: Komatsu, Kaoru R., Taya, Toshiki, Matsumoto, Sora, Miyashita, Emi, Kashida, Shunnichi, Saito, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723054/
https://www.ncbi.nlm.nih.gov/pubmed/33293523
http://dx.doi.org/10.1038/s41467-020-19699-5

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