Cargando…

Development and characterization of TrMab-6, a novel anti-TROP2 monoclonal antibody for antigen detection in breast cancer

Trophoblast cell-surface antigen 2 (TROP2) is a type I transmembrane glycoprotein that is overexpressed in a number of cancer types, including triple-negative breast cancer. The current study aimed to develop a highly sensitive and specific monoclonal antibody (mAb) targeting TROP2, which could be u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sayama, Yusuke, Kaneko, Mika K., Kato, Yukinari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723163/ https://www.ncbi.nlm.nih.gov/pubmed/33300065 http://dx.doi.org/10.3892/mmr.2020.11731

Ejemplares similares

Establishment of a novel anti-TROP2 monoclonal antibody TrMab-29 for immunohistochemical analysis
por: Sayama, Yusuke, et al.
Publicado: (2021)

An anti-TROP2 monoclonal antibody TrMab-6 exerts antitumor activity in breast cancer mouse xenograft models
por: Tanaka, Tomohiro, et al.
Publicado: (2021)

Epitope mapping of an anti-diacylglycerol kinase delta monoclonal antibody DdMab-1
por: Sano, Masato, et al.
Publicado: (2020)

The anti-epithelial cell adhesion molecule (EpCAM) monoclonal antibody EpMab-16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma
por: Hosono, Hideki, et al.
Publicado: (2020)

Epitope Analysis of an Anti-Whale Podoplanin Monoclonal Antibody, PMab-237, Using Flow Cytometry
por: Sayama, Yusuke, et al.
Publicado: (2020)

Establishment of C(20)Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells
por: Furusawa, Yoshikazu, et al.
Publicado: (2020)

Characterization of Monoclonal Antibody LpMab-3 Recognizing Sialylated Glycopeptide of Podoplanin
por: Oki, Hiroharu, et al.
Publicado: (2015)

Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C(6)Mab-13) Using 1× Alanine Scanning
por: Tanaka, Tomohiro, et al.
Publicado: (2023)

Establishment and Epitope Mapping of Anti-Diacylglycerol Kinase α Monoclonal Antibody DaMab-8 for Immunohistochemical Analyses
por: Sano, Masato, et al.
Publicado: (2020)

Development of an anti-bear podoplanin monoclonal antibody PMab-247 for immunohistochemical analysis
por: Furusawa, Yoshikazu, et al.
Publicado: (2019)

Development of a Novel Anti-CD44 Variant 4 Monoclonal Antibody C(44)Mab-108 for Immunohistochemistry
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

A Novel Anti-CD44 Variant 3 Monoclonal Antibody C(44)Mab-6 Was Established for Multiple Applications
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

Development of a Novel Anti-CD44 Variant 6 Monoclonal Antibody C(44)Mab-9 for Multiple Applications against Colorectal Carcinomas
por: Ejima, Ryo, et al.
Publicado: (2023)

PcMab-47: Novel Antihuman Podocalyxin Monoclonal Antibody for Immunohistochemistry
por: Ogasawara, Satoshi, et al.
Publicado: (2017)

Development of a Novel Anti-CD44 Variant 8 Monoclonal Antibody C(44)Mab-94 against Gastric Carcinomas
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

Development of a Novel Anti-CD44 Variant 5 Monoclonal Antibody C(44)Mab-3 for Multiple Applications against Pancreatic Carcinomas
por: Kudo, Yuma, et al.
Publicado: (2023)

Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L(1)Mab-4
por: Yamada, Shinji, et al.
Publicado: (2018)

Establishment of a Novel Anti-CD44 Variant 10 Monoclonal Antibody C(44)Mab-18 for Immunohistochemical Analysis against Oral Squamous Cell Carcinomas
por: Ishikawa, Kenichiro, et al.
Publicado: (2023)

Development of a Novel Anti-CD44 Variant 7/8 Monoclonal Antibody, C(44)Mab-34, for Multiple Applications against Oral Carcinomas
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

H(2)Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts
por: Takei, Junko, et al.
Publicado: (2020)

A Novel Anti-CD44 Variant 9 Monoclonal Antibody C(44)Mab-1 Was Developed for Immunohistochemical Analyses against Colorectal Cancers
por: Tawara, Mayuki, et al.
Publicado: (2023)

Detection of high CD44 expression in oral cancers using the novel monoclonal antibody, C(44)Mab-5
por: Yamada, Shinji, et al.
Publicado: (2018)

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C(9)Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method
por: Kobayashi, Hiyori, et al.
Publicado: (2023)

H(2)Mab-77 is a Sensitive and Specific Anti-HER2 Monoclonal Antibody Against Breast Cancer
por: Itai, Shunsuke, et al.
Publicado: (2017)

A Defucosylated Anti-EpCAM Monoclonal Antibody (EpMab-37-mG(2a)-f) Exerts Antitumor Activity in Xenograft Model
por: Asano, Teizo, et al.
Publicado: (2022)

Anti-EpCAM monoclonal antibody exerts antitumor activity against oral squamous cell carcinomas
por: Kaneko, Mika K., et al.
Publicado: (2020)

Establishment of Anti-Human ATRX Monoclonal Antibody AMab-6
por: Ogasawara, Satoshi, et al.
Publicado: (2016)

Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1
por: Liu, Xing, et al.
Publicado: (2013)

A Cancer-specific Monoclonal Antibody Recognizes the Aberrantly Glycosylated Podoplanin
por: Kato, Yukinari, et al.
Publicado: (2014)

Epitope mapping of anti-mouse podoplanin monoclonal antibody PMab-1
por: Yamada, Shinji, et al.
Publicado: (2018)

PMab-235: A monoclonal antibody for immunohistochemical analysis against goat podoplanin
por: Furusawa, Yoshikazu, et al.
Publicado: (2019)

Anti-EGFR monoclonal antibody 134-mG(2a) exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
por: Hosono, Hideki, et al.
Publicado: (2020)

Determination of critical epitope of PcMab-47 against human podocalyxin
por: Itai, Shunsuke, et al.
Publicado: (2018)

Defucosylated Monoclonal Antibody (H(2)Mab-139-mG(2a)-f) Exerted Antitumor Activities in Mouse Xenograft Models of Breast Cancers against Human Epidermal Growth Factor Receptor 2
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

Elucidation of the critical epitope of an anti-EGFR monoclonal antibody EMab-134
por: Kaneko, Mika K., et al.
Publicado: (2018)

Development of a Novel Anti-EpCAM Monoclonal Antibody for Various Applications
por: Li, Guanjie, et al.
Publicado: (2022)

A Humanized and Defucosylated Antibody against Podoplanin (humLpMab-23-f) Exerts Antitumor Activities in Human Lung Cancer and Glioblastoma Xenograft Models
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

A defucosylated anti-CD44 monoclonal antibody 5-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
por: Takei, Junko, et al.
Publicado: (2020)

Elucidation of Critical Epitope of Anti-Rat Podoplanin Monoclonal Antibody PMab-2
por: Furusawa, Yoshikazu, et al.
Publicado: (2018)

Immunohistochemical Examination of Novel Rat Monoclonal Antibodies against Mouse and Human Podoplanin
por: Kaji, Chiaki, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_fpsh88gjogi4qua70h8tmpfnop