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Inhibiting the reproduction of SARS-CoV-2 through perturbations in human lung cell metabolic network

Viruses rely on their host for reproduction. Here, we made use of genomic and structural information to create a biomass function capturing the amino and nucleic acid requirements of SARS-CoV-2. Incorporating this biomass function into a stoichiometric metabolic model of the human lung cell and appl...

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Detalles Bibliográficos
Autores principales:	Delattre, Hadrien, Sasidharan, Kalesh, Soyer, Orkun S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723300/ https://www.ncbi.nlm.nih.gov/pubmed/33234678 http://dx.doi.org/10.26508/lsa.202000869

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