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Bleomycin A5 suppresses Drp1-mediated mitochondrial fission and induces apoptosis in human nasal polyp-derived fibroblasts

Intralesional injection of bleomycin-A5 (BLE-A5) is a novel treatment for nasal polyps. Our previous study clarified that BLE-A5 could induce nasal polyp-derived fibroblast (NPDF) apoptosis in nasal polyps. However, the detailed mechanisms are still unclear. The present study aimed to determine the...

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Detalles Bibliográficos
Autores principales:	Wu, Fan, Ma, Yun, Wang, Jingyi, Ou, Huashuang, Dang, Hua, Zheng, Yiqing, Tian, Peng, Zou, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723402/ https://www.ncbi.nlm.nih.gov/pubmed/33236140 http://dx.doi.org/10.3892/ijmm.2020.4797

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