Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

Liver metabolism follows diurnal fluctuations through the modulation of molecular clock genes. Disruption of this molecular clock can result in metabolic disease but its potential regulation by immune cells remains unexplored. Here, we demonstrated that in steady state, neutrophils infiltrated the m...

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Detalles Bibliográficos
Autores principales: Crespo, María, Gonzalez-Teran, Barbara, Nikolic, Ivana, Mora, Alfonso, Folgueira, Cintia, Rodríguez, Elena, Leiva-Vega, Luis, Pintor-Chocano, Aránzazu, Fernández-Chacón, Macarena, Ruiz-Garrido, Irene, Cicuéndez, Beatriz, Tomás-Loba, Antonia, A-Gonzalez, Noelia, Caballero-Molano, Ainoa, Beiroa, Daniel, Hernández-Cosido, Lourdes, Torres, Jorge L, Kennedy, Norman J, Davis, Roger J, Benedito, Rui, Marcos, Miguel, Nogueiras, Ruben, Hidalgo, Andrés, Matesanz, Nuria, Leiva, Magdalena, Sabio, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
https://www.ncbi.nlm.nih.gov/pubmed/33287957
http://dx.doi.org/10.7554/eLife.59258

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