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TGF-β1-induced autophagy activates hepatic stellate cells via the ERK and JNK signaling pathways

Transforming growth factor β1 (TGF-β1) is one of the most important fibrogenic factors promoting the activation of hepatic stellate cells (HSCs). Autophagy is a process used by cells to degrade and recycle cellular proteins. Although TGF-β1 induces autophagy in several other cellular systems, the as...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Jiang, Na, Ping, Jian, Xu, Lieming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723502/
https://www.ncbi.nlm.nih.gov/pubmed/33236148
http://dx.doi.org/10.3892/ijmm.2020.4778