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Mitochondrial gene COX2 methylation and downregulation is a biomarker of aging in heart mesenchymal stem cells

The mitochondria have been proven to be involved in processes of aging; however, the mechansims through which mitoepigenetics affect the cytological behaviors of cardiomyocytes during the aging process are not yet fully understood. In the present study, two senescence models were constructed, replic...

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Detalles Bibliográficos
Autores principales: Sun, Xiguang, Wang, Zilong, Cong, Xiaoqiang, Lv, Yudan, Li, Zhuo, Rong, Li, Yang, Tianye, Yu, Dehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723507/
https://www.ncbi.nlm.nih.gov/pubmed/33416107
http://dx.doi.org/10.3892/ijmm.2020.4799