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JAK/STAT signaling pathway-mediated microRNA-181b promoted blood-brain barrier impairment by targeting sphingosine-1-phosphate receptor 1 in septic rats

BACKGROUND: Blood-brain barrier (BBB) impairment plays a significant role in the pathogenesis of sepsis-associated encephalopathy (SAE). However, the molecular mechanisms are poorly understood. In the present study, we aimed to investigate the regulatory relationship between the Janus kinase/signal...

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Detalles Bibliográficos
Autores principales: Chen, Sheng-Long, Cai, Geng-Xin, Ding, Hong-Guang, Liu, Xin-Qiang, Wang, Zhong-Hua, Jing, Yuan-Wen, Han, Yong-Li, Jiang, Wen-Qiang, Wen, Miao-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723536/
https://www.ncbi.nlm.nih.gov/pubmed/33313203
http://dx.doi.org/10.21037/atm-20-7024

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