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JAK/STAT signaling pathway-mediated microRNA-181b promoted blood-brain barrier impairment by targeting sphingosine-1-phosphate receptor 1 in septic rats
BACKGROUND: Blood-brain barrier (BBB) impairment plays a significant role in the pathogenesis of sepsis-associated encephalopathy (SAE). However, the molecular mechanisms are poorly understood. In the present study, we aimed to investigate the regulatory relationship between the Janus kinase/signal...
Autores principales: | Chen, Sheng-Long, Cai, Geng-Xin, Ding, Hong-Guang, Liu, Xin-Qiang, Wang, Zhong-Hua, Jing, Yuan-Wen, Han, Yong-Li, Jiang, Wen-Qiang, Wen, Miao-Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723536/ https://www.ncbi.nlm.nih.gov/pubmed/33313203 http://dx.doi.org/10.21037/atm-20-7024 |
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