Cargando…

Poncirin suppresses lipopolysaccharide (LPS)-induced microglial inflammation and ameliorates brain ischemic injury in experimental stroke in mice

BACKGROUND: Based on accumulating evidence, excessive activation of microglia-mediated inflammatory responses plays an essential role in ischemic stroke. Poncirin (Pon) exerts anti-hyperalgesic, anti-osteoporotic and anti-tumor effects on various diseases. However, the roles of Pon in microglial act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Li-Xuan, Chen, Fang-Yu, Yu, Hai-Long, Liu, Pin-Yi, Bao, Xin-Yu, Xia, Sheng-Nan, Gu, Yue, Xu, Yun, Cao, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723616/ https://www.ncbi.nlm.nih.gov/pubmed/33313089 http://dx.doi.org/10.21037/atm-20-3470

Ejemplares similares

Columbianadin Suppresses Lipopolysaccharide (LPS)-Induced Inflammation and Apoptosis through the NOD1 Pathway
por: Zhang, Chao, et al.
Publicado: (2019)

Pertussis Toxin Ameliorates Microglial Activation Associated With Ischemic Stroke
por: Zhou, Feihui, et al.
Publicado: (2020)

Oenothein B Suppresses Lipopolysaccharide (LPS)-Induced Inflammation in the Mouse Brain
por: Okuyama, Satoshi, et al.
Publicado: (2013)

Spontaneously hypertensive rats display reduced microglial activation in response to ischemic stroke and lipopolysaccharide
por: De Geyter, Deborah, et al.
Publicado: (2012)

Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice
por: Yuan, Lin, et al.
Publicado: (2016)

Monascin ameliorate inflammation in the lipopolysaccharide-induced BV-2 microglial cells via suppressing the NF-κB/p65 pathway
por: Shi, Yong-Xiang, et al.
Publicado: (2020)

Interferon-β modulates microglial polarization to ameliorate delayed tPA-exacerbated brain injury in ischemic stroke
por: Kuo, Ping-Chang, et al.
Publicado: (2023)

The Role of Microglial Phagocytosis in Ischemic Stroke
por: Jia, Junqiu, et al.
Publicado: (2022)

Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson’s Disease Models
por: Huang, Bingxu, et al.
Publicado: (2017)

Geranylgeranylacetone Ameliorates Inflammatory Response to Lipopolysaccharide (LPS) in Murine Macrophages: Inhibition of LPS Binding to The Cell Surface
por: Mochida, Shinsuke, et al.
Publicado: (2007)

α-Asarone Ameliorates Memory Deficit in Lipopolysaccharide-Treated Mice via Suppression of Pro-Inflammatory Cytokines and Microglial Activation
por: Shin, Jung-Won, et al.
Publicado: (2014)

Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo
por: Chun, Kwang-Hoon, et al.
Publicado: (2020)

Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice
por: Afridi, Ruqayya, et al.
Publicado: (2019)

Effects of Poncirin, a Citrus Flavonoid and Its Aglycone, Isosakuranetin, on the Gut Microbial Diversity and Metabolomics in Mice
por: Cao, Xuedan, et al.
Publicado: (2022)

Lipopolysaccharide Preconditioning Restricts Microglial Overactivation and Alleviates Inflammation-Induced Depressive-like Behavior in Mice
por: Yu, Haiping, et al.
Publicado: (2023)

High glucose enhances lipopolysaccharide‐induced inflammation in cultured BV2 microglial cell line
por: Hung, Hao‐Chang, et al.
Publicado: (2022)

Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway
por: Dang, Yalong, et al.
Publicado: (2016)

QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation
por: Xu, Si-Yi, et al.
Publicado: (2023)

Poncirin attenuates CCL4-induced liver injury through inhibition of oxidative stress and inflammatory cytokines in mice
por: Ullah, Hadayat, et al.
Publicado: (2020)

Brilliant blue G attenuates lipopolysaccharide-mediated microglial activation and inflammation☆
por: Lu, Kui, et al.
Publicado: (2013)

PYNOD reduces microglial inflammation and consequent neurotoxicity upon lipopolysaccharides stimulation
por: Zeng, Qi, et al.
Publicado: (2018)

Melatonin Ameliorates Inflammation and Oxidative Stress by Suppressing the p38MAPK Signaling Pathway in LPS-Induced Sheep Orchitis
por: Deng, Shou-Long, et al.
Publicado: (2020)

Cascade Signals of Papaverine Inhibiting LPS-Induced Retinal Microglial Activation
por: Zhou, Ting, et al.
Publicado: (2019)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage
por: Taylor, Roslyn A., et al.
Publicado: (2013)

Hsp22 ameliorates lipopolysaccharide-induced myocardial injury by inhibiting inflammation, oxidative stress, and apoptosis
por: Yu, Yun, et al.
Publicado: (2021)

Retraction Note: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice
por: Afridi, Ruqayya, et al.
Publicado: (2023)

Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation
por: Ngo, My-Linh, et al.
Publicado: (2009)

Suppressive Effect of Tetrahydrocurcumin on Pseudomonas aeruginosa Lipopolysaccharide-Induced Inflammation by Suppressing JAK/STAT and Nrf2/HO-1 Pathways in Microglial Cells
por: Lin, Hui-Wen, et al.
Publicado: (2022)

hUCMSCs Mitigate LPS-Induced Trained Immunity in Ischemic Stroke
por: Feng, Yi-wei, et al.
Publicado: (2020)

Serum lipopolysaccharide neutralizing capacity in ischemic stroke
por: Leskelä, Jaakko, et al.
Publicado: (2020)

Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand
por: Venkatarame Gowda Saralamma, Venu, et al.
Publicado: (2015)

Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression
por: Fang, Wen-Feng, et al.
Publicado: (2018)

Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation
por: Yahaya, M. A. F., et al.
Publicado: (2021)

Microglial Polarization: Novel Therapeutic Strategy against Ischemic Stroke
por: Xue, Yimeng, et al.
Publicado: (2021)

Exercise Preconditioning Ameliorates Cognitive Impairment in Mice with Ischemic Stroke by Alleviating Inflammation and Modulating Gut Microbiota
por: Lv, Heng, et al.
Publicado: (2022)

Amelioration of LPS-Induced Inflammation Response in Microglia by AMPK Activation
por: Chen, Chin-Chen, et al.
Publicado: (2014)

Taohong Siwu Decoction Ameliorates Ischemic Stroke Injury Via Suppressing Pyroptosis
por: Wang, Mengmeng, et al.
Publicado: (2020)

Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
por: Dong, Ze-Wu, et al.
Publicado: (2018)

Microglial VPS35 deficiency regulates microglial polarization and decreases ischemic stroke-induced damage in the cortex
por: Ye, Shi-Yang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8o0l6nrnaj6okeofrtmb7hslva