Cargando…
Pleomorphic adenoma of the trachea: A case report and review of the literature
BACKGROUND: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for ast...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723722/ https://www.ncbi.nlm.nih.gov/pubmed/33344601 http://dx.doi.org/10.12998/wjcc.v8.i23.6026 |
_version_ | 1783620402458656768 |
---|---|
author | Liao, Qian-Nuan Fang, Ze-Kui Chen, Shu-Bing Fan, Hui-Zhen Chen, Li-Chang Wu, Xi-Ping He, Xi Yu, Hua-Peng |
author_facet | Liao, Qian-Nuan Fang, Ze-Kui Chen, Shu-Bing Fan, Hui-Zhen Chen, Li-Chang Wu, Xi-Ping He, Xi Yu, Hua-Peng |
author_sort | Liao, Qian-Nuan |
collection | PubMed |
description | BACKGROUND: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for asthma for 2 years before being diagnosed with PA of the trachea. CASE SUMMARY: A 49-year-old woman was referred to our hospital due to dyspnea upon exertion and chronic cough with wheezing for 2 years. Laboratory tests showed an elevated white blood cell count, absolute neutrophil count, and percentage of neutrophils. A chest computerized tomography scan showed a well-defined, soft-tissue density lesion measuring 2.4 cm × 2.1 cm in the lower trachea. Flexible bronchoscopy revealed that nearly 90% of the tracheal lumen was obstructed. The histopathological and immunohistochemistry features suggested PA of the trachea. Furthermore, we review the characteristics of 29 patients with tracheobronchial PA over the last 30 years. CONCLUSION: Tracheobronchial PA occurs without gender predominance, mostly in the lower or upper trachea, and has a low recurrence rate. The median age at diagnosis is 48 years. The most common symptoms are cough, stridor, dyspnea, and wheezing. |
format | Online Article Text |
id | pubmed-7723722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-77237222020-12-18 Pleomorphic adenoma of the trachea: A case report and review of the literature Liao, Qian-Nuan Fang, Ze-Kui Chen, Shu-Bing Fan, Hui-Zhen Chen, Li-Chang Wu, Xi-Ping He, Xi Yu, Hua-Peng World J Clin Cases Case Report BACKGROUND: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for asthma for 2 years before being diagnosed with PA of the trachea. CASE SUMMARY: A 49-year-old woman was referred to our hospital due to dyspnea upon exertion and chronic cough with wheezing for 2 years. Laboratory tests showed an elevated white blood cell count, absolute neutrophil count, and percentage of neutrophils. A chest computerized tomography scan showed a well-defined, soft-tissue density lesion measuring 2.4 cm × 2.1 cm in the lower trachea. Flexible bronchoscopy revealed that nearly 90% of the tracheal lumen was obstructed. The histopathological and immunohistochemistry features suggested PA of the trachea. Furthermore, we review the characteristics of 29 patients with tracheobronchial PA over the last 30 years. CONCLUSION: Tracheobronchial PA occurs without gender predominance, mostly in the lower or upper trachea, and has a low recurrence rate. The median age at diagnosis is 48 years. The most common symptoms are cough, stridor, dyspnea, and wheezing. Baishideng Publishing Group Inc 2020-12-06 2020-12-06 /pmc/articles/PMC7723722/ /pubmed/33344601 http://dx.doi.org/10.12998/wjcc.v8.i23.6026 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Liao, Qian-Nuan Fang, Ze-Kui Chen, Shu-Bing Fan, Hui-Zhen Chen, Li-Chang Wu, Xi-Ping He, Xi Yu, Hua-Peng Pleomorphic adenoma of the trachea: A case report and review of the literature |
title | Pleomorphic adenoma of the trachea: A case report and review of the literature |
title_full | Pleomorphic adenoma of the trachea: A case report and review of the literature |
title_fullStr | Pleomorphic adenoma of the trachea: A case report and review of the literature |
title_full_unstemmed | Pleomorphic adenoma of the trachea: A case report and review of the literature |
title_short | Pleomorphic adenoma of the trachea: A case report and review of the literature |
title_sort | pleomorphic adenoma of the trachea: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723722/ https://www.ncbi.nlm.nih.gov/pubmed/33344601 http://dx.doi.org/10.12998/wjcc.v8.i23.6026 |
work_keys_str_mv | AT liaoqiannuan pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT fangzekui pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT chenshubing pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT fanhuizhen pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT chenlichang pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT wuxiping pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT hexi pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature AT yuhuapeng pleomorphicadenomaofthetracheaacasereportandreviewoftheliterature |