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Pleomorphic adenoma of the trachea: A case report and review of the literature

BACKGROUND: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for ast...

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Autores principales: Liao, Qian-Nuan, Fang, Ze-Kui, Chen, Shu-Bing, Fan, Hui-Zhen, Chen, Li-Chang, Wu, Xi-Ping, He, Xi, Yu, Hua-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723722/
https://www.ncbi.nlm.nih.gov/pubmed/33344601
http://dx.doi.org/10.12998/wjcc.v8.i23.6026
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author Liao, Qian-Nuan
Fang, Ze-Kui
Chen, Shu-Bing
Fan, Hui-Zhen
Chen, Li-Chang
Wu, Xi-Ping
He, Xi
Yu, Hua-Peng
author_facet Liao, Qian-Nuan
Fang, Ze-Kui
Chen, Shu-Bing
Fan, Hui-Zhen
Chen, Li-Chang
Wu, Xi-Ping
He, Xi
Yu, Hua-Peng
author_sort Liao, Qian-Nuan
collection PubMed
description BACKGROUND: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for asthma for 2 years before being diagnosed with PA of the trachea. CASE SUMMARY: A 49-year-old woman was referred to our hospital due to dyspnea upon exertion and chronic cough with wheezing for 2 years. Laboratory tests showed an elevated white blood cell count, absolute neutrophil count, and percentage of neutrophils. A chest computerized tomography scan showed a well-defined, soft-tissue density lesion measuring 2.4 cm × 2.1 cm in the lower trachea. Flexible bronchoscopy revealed that nearly 90% of the tracheal lumen was obstructed. The histopathological and immunohistochemistry features suggested PA of the trachea. Furthermore, we review the characteristics of 29 patients with tracheobronchial PA over the last 30 years. CONCLUSION: Tracheobronchial PA occurs without gender predominance, mostly in the lower or upper trachea, and has a low recurrence rate. The median age at diagnosis is 48 years. The most common symptoms are cough, stridor, dyspnea, and wheezing.
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spelling pubmed-77237222020-12-18 Pleomorphic adenoma of the trachea: A case report and review of the literature Liao, Qian-Nuan Fang, Ze-Kui Chen, Shu-Bing Fan, Hui-Zhen Chen, Li-Chang Wu, Xi-Ping He, Xi Yu, Hua-Peng World J Clin Cases Case Report BACKGROUND: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for asthma for 2 years before being diagnosed with PA of the trachea. CASE SUMMARY: A 49-year-old woman was referred to our hospital due to dyspnea upon exertion and chronic cough with wheezing for 2 years. Laboratory tests showed an elevated white blood cell count, absolute neutrophil count, and percentage of neutrophils. A chest computerized tomography scan showed a well-defined, soft-tissue density lesion measuring 2.4 cm × 2.1 cm in the lower trachea. Flexible bronchoscopy revealed that nearly 90% of the tracheal lumen was obstructed. The histopathological and immunohistochemistry features suggested PA of the trachea. Furthermore, we review the characteristics of 29 patients with tracheobronchial PA over the last 30 years. CONCLUSION: Tracheobronchial PA occurs without gender predominance, mostly in the lower or upper trachea, and has a low recurrence rate. The median age at diagnosis is 48 years. The most common symptoms are cough, stridor, dyspnea, and wheezing. Baishideng Publishing Group Inc 2020-12-06 2020-12-06 /pmc/articles/PMC7723722/ /pubmed/33344601 http://dx.doi.org/10.12998/wjcc.v8.i23.6026 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Liao, Qian-Nuan
Fang, Ze-Kui
Chen, Shu-Bing
Fan, Hui-Zhen
Chen, Li-Chang
Wu, Xi-Ping
He, Xi
Yu, Hua-Peng
Pleomorphic adenoma of the trachea: A case report and review of the literature
title Pleomorphic adenoma of the trachea: A case report and review of the literature
title_full Pleomorphic adenoma of the trachea: A case report and review of the literature
title_fullStr Pleomorphic adenoma of the trachea: A case report and review of the literature
title_full_unstemmed Pleomorphic adenoma of the trachea: A case report and review of the literature
title_short Pleomorphic adenoma of the trachea: A case report and review of the literature
title_sort pleomorphic adenoma of the trachea: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723722/
https://www.ncbi.nlm.nih.gov/pubmed/33344601
http://dx.doi.org/10.12998/wjcc.v8.i23.6026
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