SQSTM1(L341V) variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are genetically, pathologically and clinically-related progressive neurodegenerative diseases. Thus far, several SQSTM1 variations have been identified in patients with ALS and FTD. However, it remains unclear how SQSTM1 variation...

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Detalles Bibliográficos
Autores principales: Nozaki, Masahisa, Otomo, Asako, Mitsui, Shun, Ono, Suzuka, Shirakawa, Ryohei, Chen, YongPing, Hama, Yutaro, Sato, Kai, Chen, XuePing, Suzuki, Toshiyasu, Shang, Hui-Fang, Hadano, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723791/
https://www.ncbi.nlm.nih.gov/pubmed/33319079
http://dx.doi.org/10.1016/j.ensci.2020.100301

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