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Visualizing cellular heterogeneity by quantifying the dynamics of MAPK activity in live mammalian cells with synthetic fluorescent biosensors

Mitogen-Activated Protein Kinases (MAPKs) control a wide array of cellular functions by transducing extracellular information into defined biological responses. In order to understand how these pathways are regulated, dynamic single cell measurements are highly needed. Fluorescence microscopy is wel...

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Detalles Bibliográficos
Autores principales:	Ma, Min, Bordignon, Pino, Dotto, Gian-Paolo, Pelet, Serge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723811/ https://www.ncbi.nlm.nih.gov/pubmed/33319088 http://dx.doi.org/10.1016/j.heliyon.2020.e05574

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