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Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF
BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays a role in synaptic plasticity and neuroprotection. BDNF has well-established pro-survival effects, whereas its precursor protein, proBDNF, induces apoptosis. Thus, it has been suggested that the proBDNF/BDNF ratio could be an indicator of ne...
Autores principales: | Le Blanc, Jessica, Fleury, Samuel, Boukhatem, Imane, Bélanger, Jean-Christophe, Welman, Mélanie, Lordkipanidzé, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723927/ https://www.ncbi.nlm.nih.gov/pubmed/33324399 http://dx.doi.org/10.3389/fimmu.2020.575607 |
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