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Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions

Noonan syndrome is an autosomal dominant developmental disorder. Although it is relatively common, and its phenotypical variability is well documented, its pathophysiology is not fully understood. Previously, with the aim of revealing the pathogenesis of genetic disorders, we reported the induction...

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Detalles Bibliográficos
Autores principales: Hamada, Atsuko, Akagi, Eri, Obayashi, Fumitaka, Yamasaki, Sachiko, Koizumi, Koichi, Ohtaka, Manami, Nishimura, Ken, Nakanishi, Mahito, Toratani, Shigeaki, Okamoto, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723931/
https://www.ncbi.nlm.nih.gov/pubmed/33140329
http://dx.doi.org/10.1007/s11626-020-00515-9